These stem cells are collected and frozen for future use in the transplant. The machine separates your blood into different parts, including stem cells. If a transplant using your own stem cells (autologous transplant) is planned, you'll undergo a procedure called apheresis (af-uh-REE-sis) to collect blood stem cells.īefore apheresis, you'll receive daily injections of growth factor to increase stem cell production and move stem cells into your circulating blood so that they can be collected.ĭuring apheresis, blood is drawn from a vein and circulated through a machine. Collecting stem cells for autologous transplant Your transplant team will use the central line to infuse the transplanted stem cells, medications and blood products into your body. The catheter, often called a central line, usually remains in place for the duration of your treatment. In addition, a long, thin tube (intravenous catheter) will be implanted into a large vein in your chest or neck. The evaluation may take several days or more. The tests and procedures also ensure that you're physically prepared for the transplant. How you prepare Pretransplant tests and proceduresĪ series of tests and procedures can assess your general health and the status of your condition. Yellowing of the skin and the whites of your eyes.Skin changes, including scarring under the skin or skin stiffness.Chronic GVHD typically develops later and can affect many organs. It typically affects your skin, digestive tract or liver. Acute GVHD usually happens during the first months after your transplant. There are two kinds of GVHD: acute and chronic. But GVHD can happen to anyone who gets a bone marrow transplant from a donor. The risk of GVHD is greater if the stem cells come from an unrelated donor. Many people who have an allogeneic transplant get GVHD at some point. GVHD may happen at any time after your transplant. This condition occurs when the donor stem cells that make up your new immune system see your body's tissues and organs as something foreign and attack them. If you receive a transplant that uses stem cells from a donor (allogeneic transplant), you may be at risk of developing graft-versus-host disease (GVHD). Graft-versus-host disease: A potential risk when stem cells come from donors Together you can weigh the risks and benefits to decide whether a bone marrow transplant is right for you. Your health care provider can explain your risk of complications from a bone marrow transplant. Graft-versus-host disease (a complication of allogeneic transplant only).Possible complications from a bone marrow transplant include: Your risks depend on many factors, including the disease or condition that caused you to need a transplant, the type of transplant, your age and your overall health. Sometimes complications are life-threatening. Some people experience minimal problems with a bone marrow transplant, while others can have serious complications that require treatment or hospitalization. A bone marrow transplant can pose numerous risks.
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